In this review, we focused on some medicines that have already started with the repositioning for COVID-19 therapy. The repositioning clinical trials seem to be an attractive strategy, thus, the discovery of new classes of drug can be easier, the costs and time for reaching the market can decrease, the pharmaceutical supply chain is available for formulation and distribution, more therapy methods are possible by combining the drugs. We hope that the continuing studies may provide solutions for the prevention and therapy against the COVID-19 pandemic.
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