Learning Sciences of Change

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Archive for the ‘Depression’ Category

Triggering Resilience to Depression

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Researchers at the Mount Sinai School of Medicine in New York have reversed depression-like behaviors in mice in an unexpected way. Rather than silencing the hyperactive neurons that triggered the rodents’ symptoms, the team boosted their activity even further. This triggered a compensatory, self-tuning response that brought the neurons’ firing—and the rodents’ behaviors—back to normal. “There’s a saying in Chinese: If you push something to an extreme, the only way it can go is in the opposite direction,” said Ming-Hu Han, who led the study, published today April 17 in Science. Although his team needs to confirm their results in humans, Han added, “it could give us new avenues for treating depression that are conceptually very different to the classical therapeutic strategy.” Rather than identifying the cause of an illness and reversing it, it may be possible to push those causes even harder and get the body to right itself.

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Written by learningchange

18/04/2014 at 11:01

Posted in Depression

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La evolución y los desórdenes psiquiátricos

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La depresión solía tener una función adaptativa en la banda de homínidos, que se pierde en la gran ciudad, y termina volviéndose una enfermedad crónica. La depresión es una adaptación biopsicológica que evolucionó en los primates sociales, y que está asociada con varios cambios en la química del cerebro. Los niveles de serotonina bajan en primates estudiados en laboratorio que han perdido su status dentro de la jerarquía. La serotonina es un neurotransmisor que, entre otras cosas, inhibe la transmisión de los impulsos nerviosos. Es la rival de la adrenalina y de la dopamina.

Nuestro género se ha adaptado durante miles y millones de años a una vida que ha cambiado muchísimo en tan sólo unos pocos siglos. Vivir en el ambiente atestado de las ciudades es como si nos hubiesen colocado dentro de zoológicos. Esto nos predispone a enfermedades físicas y mentales. A pesar de todo lo que tenemos, la depresión es tan común que se habla de epidemia en muchos países. Pero no es la acumulación lo que nos lleva a la depresión, sino lo que hemos perdido.

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Written by learningchange

28/09/2013 at 00:07

Posted in Depression, Evolution

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A lonely heart can make you sick

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Newly divorced middle aged women are more vulnerable to contract HIV and other sexually transmitted diseases, according to Christopher Coleman, PhD, MPH, RN, associate professor at the University of Pennsylvania School of Nursing, because they tend to let their guard down with new sexual partners and avoid using protection since they are unafraid of getting pregnant.

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Written by learningchange

05/02/2012 at 13:12

Posted in Depression, Disease

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Training in ‘concrete thinking’ can be self-help treatment for depression, study suggests

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New research provides the first evidence that depression can be treated by only targeting an individual’s style of thinking through repeated mental exercises in an approach called cognitive bias modification. The study suggests an innovative psychological treatment called ‘concreteness training’ can reduce depression in just two months and could work as a self-help therapy for depression in primary care.

People suffering from depression have a tendency towards unhelpful abstract thinking and over-general negative thoughts, such as viewing a single mistake as evidence that they are useless at everything. Concreteness training (CNT) is a novel and unique treatment approach that attempts to directly target this tendency. Repeated practice of CNT exercises can help people to shift their thinking style.

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Written by learningchange

19/11/2011 at 22:45

Posted in Depression, Thinking

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